Bactericidal And Radical Scavenging Activity Of Natural Wood And Chitosan Based Novel Nanocomposite

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V. Ragul, K. S. Vinayaka, J. Madhusudhanan, P. Srinivasan, A. Shanmugarathinam, Satarupa Dey, M. I. Niyas Ahamed

Abstract

Wood is a flexible material appreciated extremely for its cost effective, great quantity, and biocompatibility. In addition, the wood materials possess prominent antibacterial properties and it can withstand efficiently when compared to other materials like glass, steel and plastics. The present study aimed to fabricate chitosan, silver nanoparticles incorporated Borassus flabelifer trichome and Prosopis juliflora wood-based biomaterial, to evaluate its antibacterial activity by broth dilution method and agar diffusion method against S. aureus, E. coli, S. typhi and B. cereus which cause digestive problems. Furthermore, in vitro free radical scavenging was performed to evaluate its ability to scavenge radicals of DPPH. The TC-Ch-AgNPs-W biocomposite showed minimum percentage of scavenging activity. It was compared with standard ascorbic acid and TC, AgNPs, Ch, W, TC-AgNPs, TC-W, TC-Chand TC-Ch-AgNPs. The efficiency of antibacterial activity of selected microorganisms and were observed around 85 % which reached up to maximum enormity. The increased antibacterial activity was significantly observed in E. coli and it was exhibited by TC-Ch-AgNPs-W.

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