Synthesis of Hydroxamic Acids and Its Characterization through Spectroscopic Techniques

Abstract

Hydroxamic acids and their derivatives have attracted considerable attention, due to their pharmacological, toxicological and pathological properties. Hydroxamic acids generally have low toxicities and have a wide spectrum of activities in all types of biological systems. The present study deals with synthesis and characterization of a series of hydroxamic acids derived from benzoylation or acylation of substituted aryl hydroxylamine or hydroxylamine hydrochloride and elemental analysis, 1H NMR, 13C NMR, and IR spectral data of the compounds.