Sungkai Leaf Extract (Peronema Canescens Jack) As Antibacterial Agent In Wound Dressing

Abstract

The leafes of the Sungkai plant (Peronema canescens Jack) is an herbal plant that contains secondary metabolites such as alkaloids, flavonoids, and tannins. The tannins that found in Sungkai leafes act as an inhibitor in bacteria. This study aims to analyze tannin content that is found in young sungkai leafes and old sungkai leafes. And then to analyze the performance of sungkai leaf extract in the making of wound dressing and measuring the distance of Staphylococcus Aureus bacteria after the addition of sungkai leaf extract and wound dressing making materials. Using UV-VIS spectrophomete, for the highest tannin yield there is a variable mass sample of young sungkai leafes 20 grams with an extraction time of 180 minutes which is 293.03ppm in young sungkai leafes and old sungkai. For samples of old sungkai leafes with a mass variable of 20 grams and extraction time of 180 minutes, there is a tannin content of 291.65 ppm.And for the performance of sungkai leaf extraction as a modern wound dreassing against staphylococcus aureus bacteria, the best combination of liquid Sodium Alginate + Glycerol + Sungkai Extract 100 % with a greater bacterial barrier distance of 13 mm compared to the combination of liquid Sodium Alginate + Glycerol + Sungkai Extract 50 %. 0 mm. Then the extraction performance on the film layer without wound dressing combination is better with 100 % Sungkai Extract variable that is 22.5 mm with positive control comparison using Amoxicillin of 33 mm.