Anti-Fungal Efficacy of Benzimidazole Analogues on Various Unicellular and Filamentous Fungi

Abstract

The focal point of the present study is the synthesis of innovative antifungal medicines that are effective against various multicellular and filamentous fungi. Benzimidazole complexes containing various substitutions were prepared and screened using agar diffusion methods for their antifungal properties. The synthesized derivatives also get confirmed with chromatographic and spectroscopic techniques. Out of ten synthesized compounds, some show significant activity, some show moderate activity and two compounds show greater activity that is similar to the antifungal activity of standard compound i.e. ketoconazole.