SARS COV 2 VIRUS: FROM PANDEMIC TO MALIGNANCY?

Abstract

Context:

Covid 19 patients present a myriad of clinical signs and symptoms with variable severity. There are many symptoms in the oral cavity; among them, the most prevalent ones are dysgeusia (taste disorders), oral pain, the exacerbation of autoimmune diseases as well as the herpes simplex virus (HSV) and varicella zoster virus (VZV) infections. Mucormycosis ,ulcerations and aphthous stomatitis are also often mentioned.

Aims:

This study aims to report few cases with oral manifestations and try to detect a pattern in them.

Settings and Design:

A series of cases of COVID-19 infection, with oral necrotic ulcers and aphthous-like ulcerations which developed early or during the course of disease after the development of dysgeusia and affected the tongue, lips, palate, and oropharynx.

Methods and Material:

The study population comprised of patients admitted in  Covid dedicated hospital in Bhopal in the age group of 20-80 years. Approval from institutional ethical committee was taken.

The sample size is 53. Informed consent was obtained from participants of the study before examination.

Results:

The CBC findings of this investigation showed high levels of CRP. This rise of CRP can be explained by the response of the human body to the new COVID-19 infection.

Conclusions:

The present study has shown the CBCs of patients with oral lesions the most likely laboratory findings in these patients were abnormalities in RBCs, WBC, CRP and D DIMER. Clinicians should consider these parameters when reading the CBC of COVID-19 patients for early diagnosis and better treatment planning