EVALUATE IMPLANT SUCCESS AND CRESTAL BONE LOSS IN IMMEDIATE AND DELAYED LOADING: A SYSTEMATIC REVIEW AND META-ANALYSIS

Abstract

Although extensive studies have been performed on immediate and delayed loading protocols and reported high success rates in the mandible, the effect of variables such as splinting, number of implants, is still unknown. The gap in the literature, the absence of a control group in most studies can make this comparison difficult. Therefore the aim of current study was evaluate implant success and crestal bone loss in immediate and delayed loading.
From the electronic databases, PubMed, Scopus, LILACS, Web of Science, EBSCO, LIVIVO, and Embase have been used to perform a systematic literature over the last ten years between 2011 and September 2021. Odds ratio and mean differences with 95% confidence interval, fixed effect model and Inverse-variance or Mantel-Haenszel method were calculated. The Meta analysis have been evaluated with the statistical software Stata/MP v.16 (The fastest version of Stata).
361 studies were selected to review the abstracts, the full text of 42 studies was reviewed. Finally, seven studies were selected. Odds ratio of Implant loss between immediate loading and delayed loading was -1.30 (OR, -1.30 95 % CI -2.17, -0.43; p=0.00) with low heterogeneity (I2 <0%; p=0.68). Mean differences of Crestal bone loss between immediate loading and delayed loading was -0.24 mm (MD, 0.24mm 95 % CI 0.21mm, 0.26mm; p=0.00).
immediate loading significantly increased the risk of implant loss before one year. Evidence shows that delayed loading preferred and is better than immediately loaded implants.